(S)-Tryptophan methyl ester

(S)-Tryptophan methyl ester - Names and Identifiers

Name	methyl L-tryptophanate
Synonyms	methyl L-tryptophanate (S)-Tryptophan methyl ester Tryptophan methyl ester hydrochloride 3-(1H-Indole-3-yl)-L-alanine methyl ester (S)-METHYL 2-AMINO-3-(1H-INDOL-3-YL)PROPANOATE (αS)-α-Amino-1H-indole-3-propanoic acid methyl ester (2S)-2-Amino-3-(1H-indole-3-yl)propanoic acid methyl ester (2S)-2-Amino-3-(1H-indole-3-yl)propionic acid methyl ester
CAS	4299-70-1
EINECS	224-309-7

(S)-Tryptophan methyl ester - Physico-chemical Properties

Molecular Formula	C12H14N2O2
Molar Mass	218.25176
Density	1.245
Melting Point	91-92℃
Boling Point	391℃
Flash Point	190℃

(S)-Tryptophan methyl ester - Upstream Downstream Industry

Raw Materials	L-Tryptophan, N,1-bis[(1,1-dimethylethoxy)carbonyl]-, methyl ester L-tryptophan monohydrochloride Tryptophan, N-benzoyl-, methyl ester (7CI) Methanol L-Tryptophan N-[(tert-Butoxy)carbonyl]-L-tryptophan
Downstream Products	(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester H-PHE-TRP-OH cis-Tadalafil

(S)-Tryptophan methyl ester - Synthesis of chiral 1,3-disubstituted -1,2,3, 4-tetrahydro-β-carboline by highly stereoselective Pictet-Spengler reaction of L-tryptophan methyl ester hydrobromide with aldehyde

From HowNet

Author:

Shaw ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(d8f6bd84d15c0a00) author:(Dong Jing)" target = "_blank"> Dong Jing ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(e0d14318d15d0e8f) author:(Hu key)" target = "_blank"> Hu key ,< A href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(99361 bf5ca03eb1) author:(Yan jingjing)" target = "_blank"> Yan jingjing , xing Jing , Shi xiaoxin

Summary:

The Pietet-Spengler reaction of L-tryptophan methyl ester hydrobromide with aldehyde was studied. The reaction was induced by a crystal process and a series of 1,3-second-generation -1,2,3, 4-tetrahydro-β-carboline compounds were synthesized with high stereoselectivity. Its structure was characterized by 1HNMR,IR,MS and elemental analysis.

keywords:

Pictet-Spengler reaction tetrahydroβ-carboline L-tryptophan chiral synthesis

DOI:

10.3969/j.issn.1005-1511.2009.06.009

cited:

Year:

2009

Last Update：2023-08-16 22:23:51

(S)-Tryptophan methyl ester - Application of 5-ferrocenyl isophthaloyl-L-tryptophan methyl ester as active carrier of hydrogen phosphate ion selective electrode

from Baidu library

patent type:

patent for invention

application (patent) number:

CN202011152652.9

date of application:

20201026

public/announcement number:

CN112285185A

date of publication/announcement:

20210129

Applicant (patentee):

Henan Urban Construction College

Inventor:

Liu Wei , Li Xia , Li yinfeng , Zhao haipeng

national and provincial code:

CN410402

Summary:

the present invention discloses the application of 5 ferrocene isophthaloyl tryptophan methyl ester as hydrogen phosphate ion selective electrode active carrier: the active carrier, plasticizer and PVC powder are dissolved in tetrahydrofuran in proportion to obtain the electrode film solution; The electrode film solution is placed at room temperature to be air-dried to obtain a PVC active film, which is sealed and bonded to the bottom of the electrode tube, 0.01mol/L KHPO solution was added as internal reference solution and inserted into AgAgCl internal reference electrode to obtain HPO ion selective electrode. The test found that when 5 ferrocene isophthaloyl tryptophan methyl ester was used as the active carrier to prepare hydrogen phosphate ion selective electrode, the detection limit of HPO ion concentration of the prepared electrode was as low as 8.4 × 10mol/L, and was less interfered by anions such as chloride ion, nitrate and sulfate ion.

Last Update：2023-08-16 22:23:51

(S)-Tryptophan methyl ester - Nature

melting point	91-92℃
boiling point	391℃
density	1.245
flash point	190℃
acidity coefficient (pKa)	17.02±0.30(Predicted)

Last Update：2024-04-09 15:16:15

Zouping Mingxing Chemical Co., Ltd.

(S)-Tryptophan methyl ester

methyl L-tryptophanate

CAS: 4299-70-1

Molecular Formula: C12H14N2O2

(S)-Tryptophan methyl ester - Names and Identifiers

(S)-Tryptophan methyl ester - Physico-chemical Properties

(S)-Tryptophan methyl ester - Upstream Downstream Industry

(S)-Tryptophan methyl ester - Synthesis of chiral 1,3-disubstituted -1,2,3, 4-tetrahydro-β-carboline by highly stereoselective Pictet-Spengler reaction of L-tryptophan methyl ester hydrobromide with aldehyde

From HowNet

Author:

(S)-Tryptophan methyl ester - Application of 5-ferrocenyl isophthaloyl-L-tryptophan methyl ester as active carrier of hydrogen phosphate ion selective electrode

from Baidu library

patent type:

(S)-Tryptophan methyl ester - Nature

Supplier List

(S)-Tryptophan methyl ester Request for Quotation

methyl L-tryptophanate

CAS: 4299-70-1

Molecular Formula: C12H14N2O2

(S)-Tryptophan methyl ester - Names and Identifiers

(S)-Tryptophan methyl ester - Physico-chemical Properties

(S)-Tryptophan methyl ester - Upstream Downstream Industry

(S)-Tryptophan methyl ester - Synthesis of chiral 1,3-disubstituted -1,2,3, 4-tetrahydro-β-carboline by highly stereoselective Pictet-Spengler reaction of L-tryptophan methyl ester hydrobromide with aldehyde

From HowNet

Author:

(S)-Tryptophan methyl ester - Application of 5-ferrocenyl isophthaloyl-L-tryptophan methyl ester as active carrier of hydrogen phosphate ion selective electrode

from Baidu library

patent type:

(S)-Tryptophan methyl ester - Nature

Supplier List

(S)-Tryptophan methyl ester